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Translating validated science into therapies.

Focused programs in tumor metabolism, precision delivery, nucleic acid therapeutics and immuno-oncology — built on dual R&D platforms and GLP/cGMP facilities.

Technology Platforms

Foundational platforms

Molecular structure — targeted delivery
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Salmonella Targeted Delivery Platform

Attenuated Salmonella (PhoP/PhoQ mutant) engineered to deliver shSTAT3/shPD-L1 gene therapy directly into the tumor microenvironment — natural tumor enrichment exceeding 1,000× normal tissue.

NeoRich quality laboratory
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mRNA Drug Platform

mRNA drugs targeting oncogenic drivers (RAS, P53, MDM2, cMYC, STAT3) for major solid tumors.

NeoRich R&D laboratory
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mRNA Vaccine Platform

mRNA cancer vaccines addressing lung, liver and colorectal cancer antigens.

Research Programs

Development programs

Our programs translate platform capabilities into disciplined drug development candidates.

1

SAL-SHP001 — Salmonella Gene Therapy

shSTAT3/shPD-L1 gene therapy for colorectal cancer — a single drug simultaneously targeting STAT3 ("de-malignancy") and PD-L1 ("immune enhancement"). Preclinical tumor growth inhibition of 6.7%–94.2% across multiple human tumor lines; 70% cure rate with no recurrence over two years in a mouse H22 orthotopic liver cancer model; favorable large-animal safety profile.

2

UCTBT

Umbilical cord mesenchymal stem cell (hUC-MSC) therapy for tuberculous destroyed lung. IIT clinical study (Phase I/IIa) with Shenzhen Third People's Hospital, combining anti-inflammatory, anti-fibrotic, immunomodulatory and lung-repair mechanisms to address an unmet need affecting more than 200,000 patients in China.

3

mRNA Drugs

mRNA therapeutics targeting RAS, P53, MDM2, cMYC and STAT3 — addressing high-unmet-need oncogenic drivers in major solid tumors.

4

mRNA Vaccines

Therapeutic mRNA cancer vaccines for lung, liver and colorectal cancer.

5

Stem Cell Orthopedic Program

Stem cell regenerative repair technology for bone and orthopedic injuries (autologous bone-marrow MSC therapy).

R&D and Production Base

GLP & cGMP-standard facilities

Biotech R&D and manufacturing laboratories meeting GLP and cGMP standards at our Shenzhen R&D base support drug development, cell preparation and technical services.

Laboratory cell culture and microscopy — NeoRich R&D base

Specialized facilities

Stem cell prep roomsImmune cell prep roomsSeed cell prep roomsPositive control prep roomsPCR testing laboratoryMicrobiology laboratoryPhysicochemical laboratory-196°C liquid nitrogen storage

Instrumentation

Ion Proton SequencerOptima XPN-100 UltracentrifugeStepOnePlus qPCRBioanalyzer 2100Milli-Q Water SystemFluorescence MicroscopyFlow CytometryCO₂ IncubatorsLive Cell WorkstationControlled-Rate Freezer

Scientific Publications

Publications

Peer-reviewed research supporting our platform technologies will be featured here as they become available.

Conference Materials

Academic conferences

Details of upcoming scientific conference presentations and investor events will be posted here.