We're assembling a team of scientists, drug developers and operators who want to do the hardest, most meaningful work in oncology.
NeoRich offers the rare combination of a foundational science platform and the agility of a small company. You'll work across disciplines — synthetic biology, nucleic acid chemistry, immunology, translational medicine — and see your work move from bench toward clinic.
We value scientific courage, operational discipline and a bias for transparent communication — the same values we bring to our shareholders.
NeoRich is hiring across CMC, regulatory, clinical, research and corporate development. Send your CV and cover letter to careers@neorich.com.
Job Responsibility: Take charge of the overall construction of CMC system for live biotherapeutic drugs (LBP) and RNA drugs. Independently establish master cell bank (MCB) and working cell bank (WCB) systems, complete strain passage stability verification, GMP production process development, process amplification and batch consistency verification. Manage CDMO cooperative projects in full cycle, formulate production quality standards and SOP systems, complete CMC data sorting and document compilation, and ensure full compliance with FDA IND and subsequent BLA application requirements. Responsible for production risk control, process optimization and cost control of microbial drugs.
Job Requirements: Master/PhD in Bioengineering, Pharmaceutical Engineering or related majors; more than 12 years of CMC development and management experience in innovative drug enterprises; familiar with GMP specifications for live biotherapeutics and RNA drugs, proficient in cell bank construction, microbial fermentation purification and drug preparation processes; experienced in FDA IND CMC declaration; rich CDMO project management experience, capable of solving complex production and quality problems independently.
Job Responsibility: Formulate global regulatory compliance strategies focusing on FDA supervision. Fully responsible for Pre-IND meeting preparation, data sorting, question simulation and official communication with FDA. Oversee the compilation, review and submission of full IND application materials, track FDA review feedback, and complete supplementary data reply. Keep track of the latest regulatory policies of global live biotherapeutics and RNA innovative drugs, establish company regulatory compliance systems, and provide professional regulatory guidance for project clinical transformation and global layout.
Job Requirements: Bachelor degree or above in Pharmacy, Biology or related majors; more than 10 years of international pharmaceutical regulatory experience, with core FDA project declaration experience; familiar with FDA regulatory rules for emerging microbial living drugs and RNA therapeutics; proficient in Pre-IND and IND full-cycle operation; have independent FDA meeting organization and response capabilities; overseas regulatory work experience is preferred.
Job Responsibility: Lead the clinical development strategy layout of oncology engineered bacteria and RNA drugs. Independently complete Phase I/II clinical trial scheme design, clinical endpoint formulation, investigator team docking and clinical overall project management. Oversee clinical trial progress, clinical safety management, clinical data collation and analysis, promote efficient progress of clinical projects, ensure clinical trial compliance and data authenticity and integrity. Responsible for clinical result output, clinical concept verification (PoC) and subsequent clinical pipeline iteration planning.
Job Requirements: Clinical Medicine, Pharmacy or related major, master degree or above; more than 12 years of clinical development management experience in oncology innovative drugs; familiar with FDA and international multi-center clinical trial specifications; rich Phase I/II clinical trial management experience in biological drugs; capable of independent clinical scheme design and clinical risk control; with successful clinical PoC verification project experience preferred.
Job Responsibility: Independently undertake the full-cycle management of GLP-standard pharmacology and toxicology research for live biotherapeutic drugs. Design in-vivo biodistribution experiments, safety pharmacology tests, inflammatory response evaluation and systemic toxicity studies, verify the safety window and in-vivo clearance mechanism of engineered bacteria drugs. Sort out preclinical safety data, form FDA-compliant toxicology research reports, effectively control preclinical safety risks, and support IND application data package construction.
Job Requirements: PhD in Pharmacology, Toxicology or related majors; more than 8 years of GLP preclinical research experience in innovative drug enterprises or CRO institutions; familiar with FDA toxicology research requirements for living microbial drugs; proficient in in-vivo pharmacological experiment design and data analysis; capable of independent project design, implementation and report summary.
Job Responsibility: Lead the core strain engineering optimization work of the platform, including strain attenuation transformation, safety switch (safety circuit) design, genetic stability verification, tumor targeting module optimization and RNA expression element transformation. Continuously iterate strain performance, improve bacterial tumor enrichment ability and in-vivo safety, eliminate genetic instability risks, and support the development and upgrading of multiple pipeline candidate drugs based on the chassis strain.
Job Requirements: PhD in Synthetic Biology, Microbiology, Genetic Engineering or related majors; more than 8 years of strain engineering research experience; proficient in gene editing, vector construction, strain transformation and stability verification; familiar with the research and development logic of tumor-targeted engineered bacteria drugs; have independent strain optimization and platform iteration capabilities.
Job Responsibility: Responsible for the full-dimensional optimization of RNA therapeutic molecules, including 5'/3' UTR regulatory element screening and optimization, codon preference optimization, mRNA secondary structure reconstruction and nucleoside chemical modification. Focus on solving core industry pain points such as easy degradation of RNA, low translation efficiency and high in-vivo immunogenicity, improve the stability and protein expression level of therapeutic RNA, and ensure the efficient and safe play of RNA drug efficacy.
Job Requirements: PhD in Molecular Biology, RNA Biology or related majors; more than 8 years of RNA molecule design and optimization experience; proficient in RNA structure prediction, chemical modification and expression regulation technology; familiar with the development rules of mRNA therapeutic drugs; capable of independent molecular optimization scheme design and effect verification.
Job Responsibility: Take charge of in-vivo pharmacodynamic verification and translational research of oncology drugs. Complete the construction and verification of mouse subcutaneous tumor model, in-situ tumor model and PDX patient-derived tumor model, evaluate the tumor suppression effect, immune microenvironment remodeling ability and tissue distribution characteristics of engineered bacteria-RNA drugs. Sort out preclinical translational data, screen core biomarkers, and provide accurate theoretical and data support for clinical trial design and patient stratification.
Job Requirements: PhD in Pharmacology, Oncology or related majors; more than 8 years of preclinical pharmacodynamic and translational research experience; proficient in various tumor animal model construction and in-vivo efficacy evaluation; familiar with tumor immune microenvironment research and clinical transformation logic; capable of docking preclinical research and clinical development.
Job Responsibility: Responsible for global business development and industrial cooperation of the company's synthetic biology + RNA delivery platform. Explore global pharmaceutical enterprise cooperation resources, promote regional licensing, co-development, technology authorization and M&A docking. Complete industry benchmarking analysis, cooperation scheme design and transaction structure negotiation, build a stable BD cooperation pipeline, realize platform technology commercialization and staged cash income, and enhance company industrial influence.
Job Requirements: Master degree or above in Biology, Pharmacy, Business Administration or related majors; more than 10 years of biomedical BD senior management experience; rich global pharmaceutical enterprise cooperation resources; familiar with biotech licensing-out/licensing-in transaction logic and valuation system; capable of independent negotiation and closing of medium and large industrial cooperation projects.
Job Responsibility: Formulate the company's global intellectual property layout strategy, complete the patent application, layout and maintenance of core technologies such as engineered strain platform, RNA optimization technology and tumor targeted delivery system. Conduct FTO freedom-to-operate analysis, screen patent risks in the industry, avoid technical infringement disputes. Build offensive and defensive patent barriers, protect the company's core platform and pipeline assets, and support long-term technological competition and capital valuation.
Job Requirements: Bachelor degree or above, with patent agent qualification or legal background preferred; more than 8 years of biomedical intellectual property management experience; familiar with synthetic biology, RNA therapy and tumor biotherapy patent layout rules; capable of independent FTO analysis, patent risk judgment and global patent layout planning.
Job Responsibility: Fully responsible for the specific implementation and site management of Phase I/II clinical trials. Complete clinical site screening, investigator docking, patient enrollment management, clinical on-site monitoring, trial progress tracking and data verification. Strictly abide by GCP specifications, ensure the standard implementation of clinical trials, complete clinical document sorting and filing, control clinical trial quality and progress, and guarantee the integrity and authenticity of clinical data.
Job Requirements: Bachelor degree or above in Clinical Medicine, Pharmacy or related majors; more than 8 years of clinical operation experience in oncology innovative drugs; proficient in GCP and international clinical trial management specifications; rich experience in Phase I/II clinical on-site management and patient enrollment; capable of independent team management and clinical project progress control.